The museum was established on June 6, 2013. From 2013 to 2017, it operated in the basement of the Center for Scientific and Technical Creativity. Since January 2017, the entire building has been transferred to the Kaluza Prison Memorial Museum.
The building was built in the mid-19th century. During the interwar period, a pre-trial detention center operated here. The greatest crimes were committed in this building during the so-called arrival of the “second soviets” in Western Ukrainian lands. Representatives of the OUN and UPA were arrested here from 1944 to the early 1950s.
Since 1960, a chemical and technological technical school has operated. The prison premises were used for practical classes for students. Since 1969, the Station of Young Technicians has been operating. In 2008, the institution was renamed the Center for Scientific and Technical Creativity of Children and Youth.
On August 25, 2018, after a major renovation, the museum was opened. The museum exposition is located in four halls: the Hall of "Archaeological Finds", the Hall of "History of the National Liberation Struggle of the Early-Mid 20th Century", the Hall of "City Room of the 50s-60s of the 20th Century", the Hall of "History of the Revolution of Dignity and the ATO/OJS". The basement is used as an exhibition space for a thematic exposition. The development and filling of two halls is ongoing.